. Author manuscript; available in PMC: 2020 Apr 17.

Published in final edited form as: Phys Med Biol. 2019 Jan 4;64(1):015015. doi: 10.1088/1361-6560/aaf400

Table 3 –

Quality indicators of dose, D_mean, D_5, and D₁₀, and number of large ionization clusters, represented by the mean, 50% and 95% quantiles ν_L,mean, ν_L(50), ν_L(95) in the rectum, and the inhomogeneity index of RBE-weighted dose in the PTV receiving 68 Gy (RBE).

Plan	D_mean [Gy (RBE)]	D₅ [Gy (RBE)]	D₁₀ [Gy (RBE)]	ν_{L, mean} [10⁶/μg]	ν_L(50) [10⁶/μg]	ν_L(95) [10⁶/μg]	QI_RBExDose
Reference plan	22.69	65.66	50.45	53.56	43.53	195.1	0.0342
Modified reference plan	12.50	57.04	33.72	26.77	11.17	158.3	0.0484
Simultaneous optimization (p_νL = 2)	14.07	62.78	40.76	30.35	13.02	181.4	0.0416
Simultaneous optimization (p_νL = 20)	11.92	51.15	28.67	24.06	11.25	131.8	0.0574