TABLE 1.
Study Cohort Demographics, Initial Illness Severity, Resource Utilization
| Patient Characteristic | Overall Study Cohort (N = 389) | Completed Baseline HRQL (N = 358) |
|---|---|---|
| Age | ||
| 0-12 months | 67 (17.2%) | 63 (17.6%) |
| 13-24 months | 40 (10.3%) | 39 (10.9%) |
| 2-4 years | 70 (18.0%) | 63 (17.6%) |
| 5-7 years | 43 (11.1%) | 38 (10.6%) |
| 8-12 years | 72 (18.5%) | 66 (18.4%) |
| 13-17 years | 97 (24.9%) | 89 (24.9%) |
| Female | 178 (45.8%) | 163 (45.5%) |
| Hispanic or Latino | 88 (22.6%) | 78 (21.8%) |
| Race | ||
| White | 234 (60.2%) | 220 (61.5%) |
| Black or African American | 80 (20.6%) | 70 (19.6%) |
| Multiracial | 13 (3.3%) | 13 (3.6%) |
| Other | 31 (8.0%) | 27 (7.5%) |
| Unknown or not reported | 31 (8.0%) | 28 (7.8%) |
| Weight at PICU admission (kg) | 389, 22 [11,42] | 358, 22 [11,42] |
| Height at PICU admission (cm) | 348, 114 [79,145] | 321, 114 [79,144] |
| Subject immunocompromised | 68 (17.5%) | 63 (17.6%) |
| Medical complexity algorithm category | ||
| Missing PHIS | 1 (0.3%) | 1 (0.3%) |
| No chronic comorbid conditions | 189 (48.6%) | 170 (47.5%) |
| Chronic comorbid conditions (non-complex) | 20 (5.1%) | 19 (5.3%) |
| Chronic comorbid conditions (complex) | 179 (46.0%) | 168 (46.9%) |
| PRISM1 | 11.0 [6.0, 17.0] | 11.0 [6.0, 17.0] |
| PELOD, First day2 | 9.0 [6.0, 11.0] | 8.0 [6.0, 11.0] |
| Hospital duration of stay (days) | 15.7 [9.2, 26.0] | 16.0 [9.4, 25.6] |
| PICU duration of stay (days) | 9.4 [5.6, 15.4] | 9.3 [5.6, 15.1] |
| Vasoactive-inotropic support duration (days) | 368, 3.0 [2.0,6.0] | 338, 3.0 [2.0,6.0] |
| Mechanical ventilation duration (days) | 380, 8.0 [5.0,14.0] | 349, 8.0 [5.0,14.0] |
PRISM data were collected during a modified period of 2 hours prior to PICU admission through 4 hours post PICU admission.
First day is defined as day of admission if admission time is before 12:00 pm or following day if admission is after 12:00 pm.
Abbreviations: HRQL, health-related quality of life survey; PICU, pediatric intensive care unit; PHIS, Pediatric Health Information System; PMCA, Pediatric Medical Complexity Algorithm category, determined using ICD 9/10 diagnosis codes up to three years prior the index sepsis admission. If no diagnostic codes were identified, the subjects were assumed to have no chronic comorbid conditions. PHIS, Pediatric Health Information System; PRISM, Pediatric Risk of Mortality, version IV; PELOD-2, Pediatric Logistic Organ Dysfunction score, version 2;
Data are presented as n (%) or n, median [Q1, Q3].