Table 2.

Comparison of serum midkine levels and other inflammation markers between Crohn’s patients and controls.

	Control group(n: 36)	Activation ofCrohn’s (n: 37)	Remission ofCrohn’s (n: 28)	P
WBC (/mm3 × 103)	6.5 ± 1.1	9 ± 3.6	7.7 ± 2.1	0.001*
Platelet (/mm3 × 103)	249 ± 62	272 ± 84	284 ± 74	0.172
CRP (mg/L)	0.3 (0.3–6.5)	1.24 (0.1–12)	0.3 (0.1–4)	<0.001**
ESR (mm/h)	8 (2–36)	21 (2–56)	13 (2–45)	0.065
Midkine	154.8 ± 76.1	281 ± 109.7	270.8 ± 90.8	<0.001***

Data are presented as median (range) or mean ± SD. *Active vs. remission, P = 0.049; active vs. control, P < 0.001; remission vs. control, P = NS. **Active vs. remission and control, P < 0.001; remission vs. control, P = 0.502. ***Control vs. active and remission, P < 0.001, active vs. remission, P = 0.666.