Table 3.

Overall accuracy and ROC analyses of midkine and other inflammation markers to differentiate activation of Crohn’s from remission.

	AUC	Sensitivity (%)	Specificity (%)	NPV (%)	PPV (%)	Overall accuracy
Midkine (cutoff: 255.5)	0.525	54.1	53.6	46.9	60.6	53.8
WBC (cutoff: 7850)	0.601	62.2	60.7	54.8	67.6	61.5
CRP (cutoff: 0.55)	0.756	77.8	83.2	74.2	84.8	78.4
ESR (cutoff: 11)	0.497	57.6	41.7	41.7	57.6	50.8
PLT (cutoff: 263500)	0.466	56.8	46.4	44.8	58.3	52.5

CRP: C-reactive protein, ESR: erythrocyte sedimentation rate, WBC: white blood cells, AUC: area under the curve, PPV: positive predictive value, NPV: negative predictive value.