Table 2.
[Dendrimer]b (mg/mL) |
t[NO]c (nmol/mg) |
t[NO]HCld (nmol/mg) |
t[dendrimer]e (μg/mg) |
|
---|---|---|---|---|
SG 80A/HP 93A-G4 octyl/NO | 5 | 1.8 ± 0.8 | 3.8 ± 0.4 | 5 ± 1 |
SG 80A/HP 93A-G4 octyl/NO | 15 | 26.0 ± 3.6 | 35.0 ± 5.2 | 42 ± 6 |
SG 80A/HP 93A-G4 octyl/NO | 25 | 72.3 ± 9.0 | 93.8 ± 7.4 | 111 ± 10 |
TP 470/SG 80A-G4 octyl/NO | 25 | 42.4 ± 4.4 | 71.1 ± 8.3 | 81 ± 6 |
TP 470/HP 93A-G4 octyl/NO | 25 | 27.3 ± 4.1 | 51.0 ± 12.7 | 63 ± 13 |
TP 470/HP 93A-G4 octylQA/NO | 25 | 44.7 ± 11.0 | 88.8 ± 18.9 | 94 ± 23 |
For all measurements, n ≥ 3 pooled experiments.
Dendrimer concentration in the original polymer solution.
Total NO payload released per mg of fiber in PBS (pH 7.4).
Total NO payload released per mg of fiber in 50 mM HCl.
Total amount of dendrimer encapsulated per mg of fiber (determined by total NO release in 50 mM HCl).