Table 2.
Patients tested for viruses, rate of detection, and turnaround time
| POCT (n=360) | Control (n=354) | Difference (95% CI) | Odds ratio (95% CI) | Number needed to test (95% CI) | p value | ||
|---|---|---|---|---|---|---|---|
| Patients tested for viruses | 360 (100%) | 158 (45%) | 55·4% (50·1 to 60·0) | .. | .. | <0·0001 | |
| Patients with any virus detected | 161 (45%) | 52 (15%) | 30·0% (23·3 to 36·8) | 4·70 (3·28 to 6·74) | 4 (2·8 to 4·2) | <0·0001 | |
| Influenza A or B | 61 (17%) | 37 (10%) | 6·5% (1·5 to 11·5) | 1·75 (1·13 to 2·71) | 16 (9 to 68) | 0·0124 | |
| Rhinovirus or enterovirus (unspecified)* | 55 (15%) | .. | .. | .. | .. | .. | |
| Coronavirus* | 18 (5%) | .. | .. | .. | .. | .. | |
| Human metapneumovirus | 14 (4%) | 5 (1%) | 2·5% (0·1 to 4·8) | .. | .. | 0·060 | |
| Parainfluenza | 11 (3%) | 2 (<1%) | 2·5% (0·6 to 4·4) | .. | .. | 0·0214 | |
| RSV | 9 (3%) | 6 (2%) | 0·8% (−1·3 to 2·9) | .. | .. | 0·60 | |
| Adenovirus | 1 (<1%) | 2 (<1%) | −0·3% (−1·2 to 0·7) | .. | .. | 0·62 | |
| Viral co-detection | 8 (2%) | 0 | 2·2% (0·7 to 3·7) | .. | .. | 0·0075 | |
| Turnaround time (h) | 2·3 (1·4)† | 37·1 (21·5) | −34·7 (−38·1 to −31·4) | <0·0001 | |||
Data are n (%) or mean (SD). Medians are presented in the appendix for completeness. POCT=point-of-care testing. RSV=respiratory syncytial virus.
*
Not tested for by laboratory PCR.
†
Assessed in 356 patients.