Table 1.
Baseline characteristics
| RCT participants (n=72) | Non-RCT participants (n=135) | ||
|---|---|---|---|
| Child | |||
| Male sex | 47 (65%) | 74 (55%) | |
| White | 70 (97%) | 130 (96%) | |
| Older children in the home at birth | 39 (54%) | 70 (52%) | |
| Sensitisation (SPT or specific IgE) | 8 (11%) | 20 (15%)* | |
| Atopic dermatitis | 21 (30%)* | 39 (30%)† | |
| 17q21 risk variant (RS2305480) | 26 (41%)‡ | 46 (39%)§ | |
| Smoking in pregnancy | 9 (13%) | 16 (12%) | |
| Cat or dog at birth | 26 (36%) | 48 (36%) | |
| Antibiotics in pregnancy | 31 (43%) | 50 (37%) | |
| Term birth >37 weeks | 67 (93%) | 127 (94%) | |
| Caesarean section | 18 (25%) | 31 (23%) | |
| Season of birth | |||
| Winter | 25 (35%) | 38 (28%) | |
| Spring | 17 (24%) | 37 (27%) | |
| Summer | 12 (17%) | 29 (21%) | |
| Autumn | 18 (25%) | 31 (23%) | |
| Mother | |||
| Maternal age at birth (years) | 31·9 (4·7) | 32·2 (4·5) | |
| Maternal asthma¶ | 31 (44%)* | 38 (28%) | |
| Maternal educational level | |||
| Low‖ | 9 (13%) | 15 (11%) | |
| Medium** | 53 (74%) | 83 (61%) | |
| High†† | 10 (14%) | 37 (27%) | |
| Household annual income | |||
| Low‡‡ | 4 (6%) | 17 (13%) | |
| Medium§§ | 45 (63%) | 73 (54%) | |
| High¶¶ | 23 (32%) | 45 (33%) | |
Data are n (%) or mean (SD). RCT=randomised controlled trial. SPT=skin prick test.
*
One child has missing information.
†
Seven children have data missing.
‡
Nine children have missing information.
§
17 children have data missing.
¶
History of doctor-diagnosed asthma.
‖
Primary school, secondary school, or college graduate.
**
Tradesman or Bachelor degree.
††
Masters degree.
‡‡
Less than €50 000.
§§
€50 000–110 000.
¶¶
More than €110 000.