Table 2 -.
Procedural and anesthetic characteristic for the first anesthetic after enrollments*
| Anesthetic Characteristics | General without N2O (N=280) | General without N2O (N=256) | ||
|---|---|---|---|---|
| Type of surgery (n=535) | ||||
| General | 72 | (26%) | 38 | (15%) |
| Orthopedic | 40 | (14%) | 97 | (38%) |
| Obstetrics/gynecology/urology | 31 | (11%) | 44 | (17%) |
| Cardiac with bypass | 33 | (12%) | 4 | (2%) |
| Neurosurgery | 10 | (4%) | 19 | (7%) |
| Vascular | 15 | (5%) | 6 | (2%) |
| Thoracic | 14 | (5%) | 1 | (0%) |
| Breast/plastic | 7 | (3%) | 17 | (7%) |
| Ear, nose, and throat/oral surgery | 18 | (6%) | 18 | (7%) |
| Other† | 39 | (14%) | 12 | (5%) |
| Duration of anesthesia (minutes) | 163 | [106, 240] | 155 | [112, 202] |
| Inhalational agents | ||||
| Isoflurane | 112 | (40%) | 141 | (55%) |
| Sevoflurane | 61 | (22%) | 50 | (20%) |
| Desflurane | 96 | (34%) | 76 | (30%) |
| Intravenous agents | ||||
| Propofol | 223 | (80%) | 236 | (92%) |
| Benzodiazepines | 137 | (49%) | 139 | (54%) |
| Sodium thiopental | 56 | (20%) | 18 | (7%) |
| Ketamine | 12 | (4%) | 13 | (5%) |
Only the first new exposure is summarized and exposures that are censored are not included. Censoring occurs at the first exposure to anesthesia of differing N2O usage (e.g. participants who have already had a new exposure to anesthesia without N2O would be censored at a new exposure to anesthesia with N2O). Categorical variables are summarized as n (%) and compared with Chi-square test. Continuous variables are summarized as mean (SD) and compared with t-tests except duration of anesthesia which is summarized as median [Q1, Q3] and compared with a rank-sum test.
Other includes cardioversion (n=14), ophthalmologic (n=12), magnetic resonance imaging (n=6), electroconvulsive therapy (n=6), interventional cardiology (n=3), wound irrigation and debridement (n=2), interventional radiology (n=2), dermatologic (n=1), endoscopy (n=1), bronchoscopy (n=1), RF/cryoablation (n=2), ureteral stent placement (n=1).