Table 1.
Demographic and Baseline Clinical Characteristics of 35 Older Adults with Major Depression and Mild Cognitive Deficits
| PATH (N=16) | ST (N=19) | |||||
| N | Perc (%) | N | Perc (%) | Fisher’s Exact (p) | ||
| Gender | 0.13 | |||||
| Female | 9 | 56.25 | 16 | 84.21 | ||
| Race and Ethnicity | 0.64 | |||||
| Caucasian | 13 | 81.25 | 17 | 89.47 | ||
| African-American | 3 | 18.75 | 2 | 10.53 | ||
| Number of Depression Episodes (>=3) | 9 | 69.23 | 9 | 56.25 | 0.70 | |
| On Antidepressants | 10 | 62.50 | 11 | 57.89 | 1.00 | |
| On Cognitive Enhancers | 1 | 6.25 | 1 | 5.26 | 1.00 | |
| Mann-Whitney Wilcoxon | ||||||
| Mean | SD | Mean | SD | z | p | |
| Age | 77.69 | 7.43 | 80.48 | 7.60 | −1.09 | 0.27 |
| Age at Onset of Depression | 53.62 | 25.19 | 56.13 | 26.11 | −0.09 | 0.93 |
| Education (years) | 14.07 | 3.01 | 13.29 | 2.95 | 1.04 | 0.30 |
| Attended Therapy Sessions# | 10.56 | 2.94 | 10.95 | 2.99 | −0.97 | 0.33 |
| MADRS Total1 | 20.31 | 3.24 | 21.11 | 3.38 | −0.63 | 0.53 |
| WHODAS-12 Total2 | 30.38 | 8.76 | 32.21 | 3.81 | −0.40 | 0.69 |
| MMSE Total3 | 28.21 | 2.16 | 28.29 | 1.05 | 0.66 | 0.51 |
| Charlson Total4 | 2.31 | 1.56 | 3.11 | 2.71 | −0.76 | 0.45 |
| Intensity of Antidepressant Medication Treatment5 | 2.00 | 1.56 | 2.00 | 1.85 | −0.26 | 0.79 |
90.5% of participants who completed the study had 12 therapy sessions, 6.3% had 11 sessions, and 3.2% had 10 session.
Montgomery Asberg Depression Rating Scale (MADRS)
World Health Organization Disability Assessment Schedule – II - 12 items
Mini Mental State Exam – Total
Charlson Commorbity Index
Composite Antidepressant Score (CAD) – Revised.