Figure 4:

(A) Spearman rank correlation coefficient matrix of the single-sample Gene set enrichment analysis scores and the radiomic features extracted from the GBM tumor habitat (necrotic core, enhancing tumor and peri-tumoral edema). ‘*’ signifies a statistically significant (p<0.05) relationship (B) Top row – Gabor wavelet based radiomic features extracted from the peri-tumoral edema region of the GBM tumor habitat was found to be positively correlated with the cell differentiation and proliferation biological process. Bottom row – Shape feature ‘Elongation’ of the peri-tumoral edema was found to be positively correlated with angiogenesis and cell proliferation biological processes.