Skip to main content
. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Brain Imaging Behav. 2020 Apr;14(2):369–382. doi: 10.1007/s11682-019-00245-x

Fig. 1a. Effects of entorhinal CT, CBF, and APOE on memory change.

Fig. 1a.

Three-way interaction plot with simple slopes (mean ±1SD) showing that the relationship between baseline entorhinal CBF and memory change differs significantly by APOE genotype and CT, such that lower baseline entorhinal CBF is associated with greater memory decline, but only among ε4 carriers with lower baseline entorhinal CT, with higher CT appearing relatively protective against future cognitive decline. Note: EC= Entorhinal cortex; APOE= Apolipoprotein E gene; CBF= Cerebral blood flow; CT= Cortical thickness; std= Z-score standardization; SD= standard deviation; t= t-statistic; p= p-value; **Simple slope significance at p<0.01; simple slope significance at p<0.001