Table 3.
Regional and total cerebellar volumes in premature infants and controls at MRI-1 (top row) and MRI-2 (bottom row), adjusting for gestational age at MRI. LH= left hemisphere, RH=right hemisphere, LDN=left dentate nucleus, RDN=right dentate nucleus, AV=anterior vermis, NV= neo vermis, PV=posterior vermis, and CBL=cerebellum.
LH | RH | LDN | RDN | AV | NV | PV | Total CBL | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | ||
MRI-1 | Control Fetuses (38 scans) | 5.43 | <.0001* | 5.43 | <.0001* | 0.15 | 0.43 | 0.14 | 0.22 | 0.43 | 0.63 | 0.37 | 0.42 | 0.31 | 0.71 | 12.27 | <.0001* |
MRI-2 | Control Infants (38 scans) | 9.83 | 0.0005 * |
9.92 | 0.0001 * |
0.21 | 0.04* | 0.20 | 0.01* | 0.60 | 0.03* | 0.50 | 0.005* | 0.45 | 0.06 | 21.72 | 0.0008 * |
Results of least squares means estimates from generalized linear model, controlling for gestational age at MRI.
MRI-1 denotes the timepoint of the third trimester (either in utero or ex utero in the early postnatal period following preterm birth);
MRI-2 denotes the timepoint of term equivalent age;
Significant after adjusting for multiple testing.