Table 4.
Comparison of regional and total cerebellar volumes in premature infants and controls at MRI-1 and MRI-2, adjusting for gestational age at MRI and total brain volume.
LH | RH | LDN | RDN | AV | NV | PV | Total CBL | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | Mean | p | ||
MRI-1 | Control Fetuses (38 scans) | 5.08 | 0.09 | 5.08 | 0.12 | 0.14 | 0.63 | 0.14 | 0.72 | 0.40 | 0.19 | 0.35 | 0.51 | 0.30 | 0.30 | 11.50 | 0.17 |
MRI-2 | Control Infants (38 scans) | 9.08 | 0.34 | 9.18 | 0.65 | 0.20 | 0.99 | 0.19 | 0.91 | 0.58 | 0.01* | 0.50 | 0.03 | 0.44 | 0.008* | 20.18 | 0.29 |
Results of least squares means estimates from generalized linear model, controlling for gestational age at MRI and total brain volume.
MRI-1 denotes the timepoint of the third trimester (either in utero or ex utero in the early postnatal period following preterm birth);
MRI-2 denotes the timepoint of term equivalent age;
Significant after adjusting for multiple testing.