Table 2.
Comparison of laboratory parameters between CVD and non-CVD COVID-19 patients.
| Normal Range | Median (IQR) |
||||
|---|---|---|---|---|---|
| Total (n = 83) | Non-CVD (n = 41) | CVD (n = 42) | P Valuea | ||
| HBDH (U/L) | 72–182 | 154 (134.5–205.0) | 142 (125.5–167.5) | 176 (146.5–226.0) | <0.01 |
| ALT (U/L) | 5–35 | 21.5 (16–33.25) | 19 (14.5–31.5) | 26 (17–42) | <0.01 |
| LDH (U/L) | 109–245 | 207 (178.5–282) | 187 (173–229) | 258 (205.75–321.75) | 0.01 |
| GGT (U/L) | 11–50 | 16 (12.5–26.5) | 13 (11–16) | 24.5 (16–47.5) | <0.01 |
| AST (U/L) | 8–40 | 23 (19–28.5) | 21.5 (17–26) | 26 (21.5–45.5) | 0.03 |
| ALP (U/L) | 40–150 | 56 (47–73) | 50 (46–63) | 64 (55–81) | <0.01 |
| CK (U/L) | 38–174 | 63 (47–90.5) | 57 (41.5–74.5) | 76.5 (54.75–109) | <0.01 |
| SAA (mg/dL) | <10 | 47.35 (5.23–430.83) | 15.7 (3.8–73.1) | 339.4 (34.55–692.95) | <0.01 |
| TP (mg/L) | 64–83 | 64.85 (59.53–70.68) | 68.75 (63.85–72.775) | 60.75 (57.675–65.3) | <0.01 |
| Prealbumin (mg/L) | 0.17–0.42 | 0.208 (0.14–0.25) | 0.212 (0.2–0.25) | 0.166 (0.12–0.23) | 0.02 |
| ALB (mg/L) | 35–55 | 39.25 (35.98–42.53) | 41.4 (39.25–43.7) | 36.9 (34.4–38.9) | <0.01 |
| ALB/GLB | 1.5–2.5 | 1.6 (1.3–1.8) | 1.6 (1.4–1.8) | 1.5 (1.2–1.8) | 0.53 |
| Lymphocytes (×109/L) | 1.1–3.2 | 1.15 (0.695–1.545) | 1.4 (1.08–1.81) | 0.805 (0.47–1.173) | <0.01 |
| Neutrophils (×109/L) | 1.8–6.3 | 2.78 (2.015–4.115) | 2.55 (2.01–3.22) | 3.23 (2.023–5.7) | 0.03 |
| RBC (×1012/L) | 3.8–5.1 | 4.16 (3.87–4.44) | 4.3 (4.09–4.66) | 3.94 (3.763–4.218) | <0.01 |
| Hemoglobin (g/dL) | 115–150 | 124 (117–135) | 132 (119–141) | 120 (115–129) | <0.01 |
| CRP (mg/L) | <8 | 9.625 (3.14–34.95) | 5.575 (3.14–13) | 21.35 (6.143–85.825) | <0.01 |
| Serum ferritin (ng/ml) | 21.8–275 | 294.35 (88.28–713.85) | 99.9 (55.9–185.8) | 539.6 (313.1–914.5) | <0.01 |
| ESR (mm/h) | <15 | 18.5 (7–40) | 10 (7–24) | 48 (25–76) | <0.01 |
| IL-6 (pg/ml) | 0.1–2.9 | 6.69 (3.33–15.535) | 3.69 (2.963–9.72) | 13.73 (6.56–24.13) | <0.01 |
| IL-10 (pg/ml) | 0.1–5 | 4.03 (3.425–4.75) | 3.58 (3.173–4.268) | 4.54 (3.75–4.83) | <0.01 |
| D-dimer (μg/L) | <0.5 | 0.41 (0.22–1.125) | 0.28 (0.22–0.348) | 1.105 (0.435–1.548) | <0.01 |
| FIB (g/L) | 2.0–4.0 | 4.01 (3.235–5.27) | 3.505 (2.82–4.07) | 5.01 (3.965–6.135) | <0.01 |
Abbreviation: IQR, interquartile range; COVID-19, coronavirus disease 2019; HBDH, α-Hydroxybutyrate Dehydrogenase; ALT, alanine aminotransferase; LDH, lactic dehydrogenase; GGT, γ-glutamyltransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; CK, creatine kinase; SAA, serum amyloid A; TP, total protein; ALB, albumin; GLB, globulin; RBC, red blood cells; CRP, c-reactive protein; ESR, erythrocyte sedimentation rate; FIB, fibrinogen.
a
P values indicate differences between CVD and non-CVD patients. P < 0.05 was considered statistically significant.