Table 3.
Association of oral cavity cancer with smokeless tobacco (SLT) use in study subjects.
| Variables | Cases(n = 90) | Controls(n = 120) | Unadjusted OR | 95% CI | Adjusted ORa | 95% CIa | Adjusted ORb | 95% CIb |
| SLT users | 58 | 32 | 4.98 | 2.76–9.01 | 4.71 | 2.53–8.74 | 28.29 | 9.93–80.52 |
| Never user | 32 | 88 | 1.00 (referent) | - | 1.00 (referent) | - | 1.00 (referent) | |
| Type of SLT used: | ||||||||
| Snuff | 36 | 20 | 4.95 | 2.51–9.77 | 4.82 | 2.37–9.80 | 32.65 | 10.6–100.4 |
| Betel leaf | 16 | 8 | 5.50 | 2.15–14.08 | 4.42 | 1.66–11.91 | 23.18 | 6.23–86.2 |
| Supari/chalia | 6 | 4 | 4.12 | 1.09–15.57 | 4.67 | 1.14–19.12 | 21.09 | 3.59–123.6 |
| Never users | 32 | 88 | 1.00 (referent) | - | 1.00 (referent) | - | 1.00 (referent) | - |
| Duration of snuff use: | ||||||||
| <10 years | 10 | 5 | 3.70 | 1.20–11.4 | 5.45 | 1.59–18.71 | 21.44 | 4.89–94.01 |
| 10–20 years | 4 | 6 | 1.23 | 0.33–4.56 | 1.73 | 0.43–6.99 | 5.81 | 1.23–27.45 |
| >20 years | 22 | 9 | 4.52 | 1.95–10.52 | 3.25 | 1.37–7.71 | 6.45 | 2.50–16.65 |
| Never users | 54 | 100 | 1.00 (referent) | - | 1.00 (referent) | - | 1.00 (referent) | - |
| Frequency of snuff use: | ||||||||
| Daily | 5.22 | 2.66–10.27 | 5.22 | 2.56–10.65 | 34.5 | 11.2–106.1 | ||
| Frequently in a week | 6.60 | 2.16–20.2 | 6.80 | 2.09–22.1 | 45.8 | 9.74–216.1 | ||
| Weekly | 5.50 | 0.961–31.5 | 4.82 | 0.76–30.4 | 32.4 | 3.64–287.8 | ||
| Frequently in a month | 2.20 | 0.56–8.71 | 1.43 | 0.35–5.83 | 5.48 | 0.97–31.03 | ||
| No | 1.00 (referent) | - | 1.00 (referent) | - | 1.00 (referent) | - | ||
a: OR adjusted for age (≤50 and >50 years) and smoking (never vs. ever smokers). b: OR adjusted for age (≤50 and >50 years), gender, and smoking (never vs. ever smokers).