Table 1.
Baseline characteristics of study population∗.
| Groups | TBLB group | R-EBUS-TBLB group | t/χ2 value | P value |
|---|---|---|---|---|
| Particients | 60 | 61 | ||
| Age ± 2SD (years) | 55.8 ± 12.5 | 55.4 ± 11.5 | 1.168 | 0.243 |
| Male/female | 38/22 | 36/25 | 0.237 | 0.626 |
| Immunodeficiency | ||||
| Hematological malignancy | 34 (56.7) | 36 (59.0) | 0.068 | 0.794 |
| Lesion location n% | ||||
| Lower lobe | 27 (45.0) | 33 (54.1) | 2.524 | 0.283 |
| Right upper lobe | 16 (26.7) | 18 (29.5) | ||
| Left upper lobe | 17 (28.3) | 10 (16.4) | ||
| Leision size | ||||
| ≤3 cm | 19 (31.7) | 18 (29.5) | 0.066 | 0.797 |
| >3 cm | 41 (68.3) | 43 (70.5) | ||
| Distance from the chest wall | ||||
| ≤3 cm | 22 (36.7) | 28 (45.9) | 1.064 | 0.302 |
| >3 cm | 38 (63.3) | 33 (54.1) | ||
| CT findings | ||||
| Nodule or cavitation | 19 (31.7) | 28 (45.9) | 2.720 | 0.257 |
| Confluent or patchy consolidation | 29 (48.3) | 22 (36.1) | ||
| GGO | 12 (20.0) | 11 (18.0) | ||
| Complications | ||||
| Mild bleeding | 2 (3.3) | 1 (1.6) | 0.359 | 0.549 |
| Pneumothorax | 2 (3.3) | 1 (1.6) | 0.356 | 0.551 |
| Final diagnosis | ||||
| Bacteria (mycobacteria excluded) | 30 (50) | 33 (54.1) | ||
| Virus | 12 (20) | 11 (18) | ||
| Fungus | 18 (30) | 21 (34.4) | ||
| Atypical pathogen | 6 (10) | 7 (11.5) | ||
| MTBC | 9 (15) | 10 (16.4) | ||
| Positivity of mNGS | 36 (60.0) | 48 (78.7) | 4.977 | 0.026 |
GGO, ground-glass opacity. MTBC, mycobacterium tuberculosis complex. ∗Data are presented as no. (%) or mean ± SD unless otherwise indicated.