Table 4.
Reports of surgical resection for recurrent/ progressive brain metastases after STI
| First Author, Year [ref] | Number of patients | Surgical lesion | RPA class population I/2/3 (%) | Previous treatment | Median tumor volume or maximum diameter | Rates of radiation necrosis alone (%) | Median survival (months) | # Pts with local recurrence after surgery (%) | # Pts with dissemination after surgery (%) | Surgical mortality (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| Vecil, 2005 [17] | 61 | 74 | 13/72/15 | SRS | NR | 6/74 (8) | 11.1 | 13/ 74 (17.6) | NR | 3.0 |
| Truong, 2006 [10] | 32 | 32 | 13/87/0 | SRS | 1.5 cc | 4/32 (12.5) | 8.9 | 9/ 32 (28) | NR | 3.0 |
| Kano, 2009 [18] | 58 | 58 | 38/52/10 | SRS | 15.5 cc | 0 (0) | 7.6 | 18/ 58 (31) | NR | 1.7 |
| Jagannathan, 2010 [11] | 15 | 15 | NR | SRS | 7.5 cc | 5/15 (33.3) | 11.3 | 0/ 15 (0) | NR | NR |
| Schackert, 2013 [19] | 67 | 67 | 24/46/30 | SRS | NR | NR | 7.5 | 21/ 67 (31.3) | NR | NR |
| Telera, 2013 [20] | 15 | 16 | 50/25/25 | SRS | 3 cm (1.5–4.5) | 7/16 (50) | 19.0 | 0/16 (0) | NR | 0.0 |
| Present study, 2019 | 48 | 54 | 13/31/56 | SRS or SRT | 3.5 cm | 7/54 (13) | 20.2 | 14/54 (25.6) | 3/54 (5.6) | 0.0 |
*NR Not reported,
# Pts patients