Fig. 4.

Pharmacologic inhibition of sEH abolishes obesity-induced adipose inflammation via gut bacteria-dependent mechanisms. (A) FACS quantification of CD45⁺ immune cells in gonadal adipose tissue (n = 5 mice per group). (Left) Representative FACS images. (Right) Quantification of immune cells in adipose tissue. (B) Gene expression of Tnf-α, Mcp-1, and Tlr-4 in gonadal adipose tissue (n = 8 to 10 mice per group). (C) Representative H&E histology of gonadal adipose tissue. The data are mean ± SEM. (Scale bars: 50 μm.)