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. 2020 Apr 3;117(15):8225–8227. doi: 10.1073/pnas.2003702117

Fig. 1.

Fig. 1.

Summary of CRISPRi screens performed by Raffeiner et al. (7) using variants of catalytically dead Cas9 (dCas9, gray) fused to various domains of adapter proteins that recruit transcriptional repressors. For comparison, wild-type Cas9 (green) is also displayed, but CRISPR screens were not performed. KRAB domain of POGK, kPOGO.