Figure 2.
Cross‐reactive CD8+ T‐cell matrix. The Epstein – Barr virus BMLF1280 peptides induce CD8+ T‐cell responses that cross‐react with four other CD8+ T‐cell populations. The influenza M158 peptide can induce CD8+ T‐cell responses that cross‐react with at least three other CD8+ T‐cell populations. Which cross‐reactive pattern any individual displays depends on the private specificity of each individual's T‐cell receptor repertoire. The numbers in the figure indicate how many individuals of the total tested demonstrated the predominant cross‐ reactive response indicated (the thickness of arrows correlates with the frequency).