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. 2010 Jun 15;236(1):125–138. doi: 10.1111/j.1600-065X.2010.00912.x

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© 2010 John Wiley & Sons A/S

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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Longitudinal analysis of antigen‐specific antibody responses in two representative subjects. Antigen‐specific serum antibody responses were followed in two subjects from the Oregon National Primate Research Center (ONPRC) cohort (1) and show the durability of humoral immunity during middle age (Subject 1) and more advanced age (Subject 2). Both subjects were vaccinated against tetanus and diphtheria, and Subject 1 also received smallpox vaccination (i.e. vaccinia virus infection). Antibody responses were determined by ELISA as previously described (1). VZV, varicella‐zoster virus; EBV, Epstein–Barr virus.

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