Figure 5.

The cytokine milieu impacts the TLR3‐driven enhancement of IL‐10. WT microglial cells were stimulated for 24 hr with TLR2 or TLR3 agonists alone or in combination in the absence or presence of increasing doses of (a) IL‐17 or (b) IFN‐γ. Cell culture supernatants were collected and IL‐10 production was measured by ELISA. Represented are the mean ± SD for triplicate wells per condition for two independent experiments. Statistical differences were assessed by student's t test or one‐way ANOVA. Significant statistical differences are represented by *** p < .001. bdl, below detection level