Table 2.
Properties of lymphocytes
Cells | Receptors | CD marker | Type | Role | Secreted products |
---|---|---|---|---|---|
B | IgM, IgD | − | − | Cells are activated via these receptors | − |
T | α,β or γ,δ | CD4 | Th‐2 | Helps B cells make antibodies and certain cytokines | IgM, IgG, IgA, IgE Mainly IL −4, −5, −6, −10 |
α,β or γ,δ | Th‐1 | Helps B cells make antibodies and certain cytokines | Some subclasses of IgG IL −2, IFNγ, TNFα, β | ||
α,β or γ,δ | Th‐1 | Helps differentiation of CD8+ T cells | |||
α,β or γ,δ | Th‐1 | Mediates DTH responses | |||
α,β | CD8 | Lyses‐infected cells | IL −2, IFNγ, TNFα |
DTH, delayed‐type hypersensitivity; IFN, interferon; IgA, immunoglobin A; IgD, immunoglobin D; IgE, immunoglobin E; IgG, immunoglobin G; IgM, immunoglobin M; IL, interleukin; TNF, tumour necrosis factor.10