Table 1.
Demographic and clinical characteristics of staff persons, and results of serological surveillance
| ID | Sex, age, country of birth | Smallpox vaccination | Role in the farm | Comorbidities | Exposure to diseased monkeys | Symptoms | IFA virus target | IgGa on Jan. 22, 2015 | IgMa on Jan. 22, 2015 | IgGa6 weeks later | IgMa6 weeks later | IgGa 12 weeks later | IgMa 12 weeks later |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M, 69, Italy | Yes | Coordinator | No | Yes (Direct assistance) | No | VL | 1:80 | <1:20 | 1:80 | <1:20 | ||
| OPV Abatino | 1:80 | <1:20 | 1:40 | <1:20 | |||||||||
| 2 | M, 35, Italy | No | Veterinary | No | Yes (Direct assistance including intubation) | Fever, general malaise, asthenia | VL | <1:40 | <1:20 | <1:40 | <1:20 | ||
| OPV Abatino | <1:40 | <1:20 | <1:40 | <1:20 | |||||||||
| 3 | M, 34, Albania | Yes | Maintenance staff | No | No | No | VL | Weak positive | <1:20 | Weak positive | <1:20 | ||
| OPV Abatino | 1:20 | <1:20 | 1:20 | <1:20 | |||||||||
| 4 | F, 37, Italy | No | Researcher | No | Yes (Direct assistance, removal of dead bodies) | Fever, sore throat | VL | <1:40 | <1:20 | <1:40 | <1:20 | ||
| OPV Abatino | <1:40 | <1:20 | <1:40 | <1:20 | |||||||||
| 5 | F, 37, Italy | No | Researcher | No | No | No | VL | <1:40 | <1:20 | <1:40 | <1:20 | ||
| OPV Abatino | <1:40 | <1:20 | <1:40 | <1:20 | |||||||||
| 6 | M, 38, Italy | No | Researcher | Thyroidectomy | Yes (Direct assistance, removal of dead bodies) | No | VL | 1:20 | <1:20 | 1:160 | 1:20 | 1:320 | 1:40 |
| OPV Abatino | 1:20 | <1:20 | 1:320 | 1:40 | 1:640 | 1:40 | |||||||
| 7 | F, 61, Albania | Yes | Maintenance staff | Hypertension | No | No | VL | Weak positive | <1:20 | 1:40 | <1:20 | ||
| OPV Abatino | 1:20 | <1:20 | 1:20 | <1:20 | |||||||||
| 8 | F, 27, Italy | No | Researcher | No | No | No | VL | <1:20 | <1:20 | <1:40 | <1:20 | ||
| OPV Abatino | <1:20 | <1:20 | <1:40 | <1:20 | |||||||||
| 9 | F, 29, France | No | Researcher | No | No | No | VL | <1:20 | <1:20 | ND | ND | ||
| OPV Abatino | <1:20 | <1:20 | |||||||||||
| 10 | F, 38, Italy | No | Maintenance staff | No | No | No | VL | <1:40 | <1:20 | <1:40 | <1:20 | ||
| OPV Abatino | <1:40 | <1:20 | <1:40 | <1:20 | |||||||||
| 11 | F, 67, Italy | Yes | Assistant | Rheumatoid arthritis | No | No | VL | 1:80 | <1:20 | 1:80 | <1:20 | ||
| OPV Abatino | 1:80 | <1:20 | 1:80 | <1:20 |
ND, not done.
The IFA titre was established as the last serum dilution showing appreciable immunofluorescent staining.
a
The antibody titre was determined by IFA against LV and OPV Abatino.
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