Table 5.
Viruses used in validation studies at CSL Behring for Haemate P/ Humate‐P (in accordance with CPMP/ BWP/268/95) [1].
| Transfusion relevant virus | Test virus (model virus) | Genome | Enveloped | Size (nm) | Resistance to treatment |
|---|---|---|---|---|---|
| HIV | HIV‐1 | RNA | Yes | 80–100 | Low |
| HCV | BVDV | RNA | Yes | 50–70 | Low |
| HBV | None available* | DNA | Yes | 45 | Medium |
| HAV | HAV | RNA | No | 25–30 | High |
| B19V | CPV | DNA | No | 18–24 | Very high |
| – | Herpesvirus (non‐specific model) | DNA | Yes | 120–200 | Medium |
B19V, parvovirus B19; BVDV, bovine viral diarrhoea virus; CPV, canine parvovirus; HAV, hepatitis A virus; HBV, hepatitis B virus; HCV, hepatitis C virus; HIV‐1, human immunodeficiency virus 1.
*According to CPMP/BWP/269/95 [26].