Figure 1.
Specific anti‐PEDV antibody titres in the serum and milk collected from pregnant sows after prime‐boost immunizations. (a) Serum was collected from the pregnant sows of all groups on days 0, 21 and 35 post first immunization, and was assayed for anti‐PEDV‐specific IgG antibodies through ELISA. (b) Milk was collected from the pregnant sows of all groups on day 1 postfarrowing and was assayed for anti‐PEDV‐specific IgA antibodies through ELISA. Data are represented as mean ± SD, n = 5. * stand for P < 0·05, and *** stand for P < 0·001. Groups: (○) DMEM + DMEM; (△) PEDV + PEDV; (□) coated PEDV‐loaded microspheres + coated PEDV‐loaded microspheres; (●) PEDV + inactivated PEDV vaccines; (▲) coated PEDV‐loaded microspheres + inactivated PEDV vaccines; (■) inactivated PEDV vaccines + inactivated PEDV vaccines