Figure 4.

HAV‐ and HCV‐RNA replication are sensitive toward an overlapping set of inhibitors. (A‐F) Huh7‐Lunet cells were electroporated with subgenomic HAV or HCV (JFH, Con1, and H77) luciferase reporter replicons. First, 4 hours p.t., different compounds were added at indicated concentrations. Then, 48 hours p.t., cells were lysed and luciferase activity was measured. Data are derived from two independent experiments performed with triplicates and depicted in logarithmic scale. Graphs present mean and standard deviation of r.l.u. normalized to untreated controls (n = 2). Abbreviations: p.t., post‐transfection; r.l.u., relative light units.