Table 1.
Organ‐specific manifestations in the pre‐HAART era
| Organ | Organ‐specific manifestations | |
|---|---|---|
| High frequency | Moderate or low frequency | |
| Lung | PCP | Bacterial pneumonia |
| CMV pneumonia | ||
| Mycobacterial infection | ||
| Brain | Toxoplasma encephalitis | HIV‐1 encephalitis |
| HIV‐1 encephalitis | CMV infection | |
| Progressive multiple leukoencephalopathy | ||
| Heart | Pericarditis | Focal myocarditis |
| Pulmonary hypertension | ||
| Kidney | Focal glomerulosclerosis | Membrane and proliferative glomerulonephritis |
| (HIVAN) | Minimal‐change glomerulonephritis | |
| Gut | Candidal and CMV oesophagitis | Enterocolitis (CMV, Cryptosporidium spp. and |
| Salmonella spp.) | ||
| Liver | Mycobacterial hepatitis | CMV hepatitis |
| Drug‐induced hepatitis | ||
| Non‐Hodgkin lymphoma | ||
| Oral cavity and skin | Oral candidiasis | Bacterial cutaneous infections |
| Seborrheic dermatitis | Molluscum contagiousum | |
| Psoriasis | ||
| Atopic dermatitis | ||
| Eye | Retinal microvasculopathy | CMV retinitis |
| Toxoplasma retinochoroiditis | ||
| Cutaneous and mucosal system, and lymph nodes | Kaposi's sarcoma | Multicentric Castleman's disease |
| Non‐Hodgkin lymphoma | Body cavity lymphoma | |
| Hodgkin disease | ||
CMV, cytomegalovirus; PCP, Pneumocystis carinii pneumonia.