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. 2009 Aug 17;126(9):2153–2163. doi: 10.1002/ijc.24836

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Copyright © 2009 UICC

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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cDNA microarray analysis revealed a markedly enhanced expression of FOXM1 mRNA in intrahepatic cholangiocarcinoma tissues. (a) A list of up‐regulated genes in intrahepatic cholangiocarcinoma tissue. These genes exhibited greater than 4‐fold increased expression in cancer cells in comparison to their normal counterparts in more than 15 out of 25 intrahepatic cholangiocarcinoma patients. The expression of FOXM1 mRNA in intrahepatic cholangiocarcinoma tissue specimens was markedly enhanced in 24 of 25 patients with intrahepatic cholangiocarcinoma. (b) The expression levels of FOXM1 in the normal tissues were far lower than those in non‐small cell lung carcinoma (NSCLC) or esophageal cancer tissues based on the cDNA microarray analysis.