Table 2.
Treatments and outcomes of 10 kidney transplant recipients infected with COVID-19.
| Patient |
n | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ||
| Clinical condition | |||||||||||
| Mild | Yes | – | – | – | – | – | Yes | – | – | – | 2 |
| Severe | – | – | Yes | Yes | Yes | – | – | Yes | – | Yes | 5 |
| Critical | – | Yes | – | – | – | Yes | – | – | Yes | – | 3 |
| IS adjustment | |||||||||||
| M/Mi cessation | No | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | 9 |
| Days of M/Mi cessation | – | 12 | 30 | 21 | 20 | 24 | 12 | 14 | 11 | 18 | – |
| CNI cessation | No | No | No | Yes | Yes | Yes | Yes | Yes | Yes | Yes | 7 |
| Days of CNI cessation | – | – | – | 6 | 9 | 14 | 7 | 7 | 11 | 8 | – |
| CNI reduction | No | Yes | No | Yes | Yes | Yes | Yes | Yes | Yes | Yes | 8 |
| Days of CNI reduction | – | 12 | – | 15 | 5 | 8 | 7 | 5 | 11 | 10 | – |
| Use of corticosteroid | No | No | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | 8 |
| MP i.v. dose (mg/d) | – | – | 20 | 40 | 20 | 40 | 40 | 40 | 40 | 20 | – |
| Days of MP i.v. | – | – | 2 | 9 | 9 | 19 | 12 | 10 | 5 | 10 | – |
| Use of IVIG | No | Yes | No | Yes | Yes | Yes | Yes | No | Yes | Yes | 7 |
| Antiviral therapy | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | 10 |
| Oxygen support | |||||||||||
| Nasal cannula | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | 10 |
| Noninvasive ventilation | No | Yes | No | No | No | Yes | No | No | Yes | No | 3 |
| Outcomes | |||||||||||
| Discharge | Yes | Yes | Yes | Yes | Yes | No | Yes | Yes | Death | Yes | 8 |
| Onset to shedding (d) | 37 | 45 | 25 | 29 | 30 | – | 15 | 22 | – | 24 | – |
| Hospital stay (d) | 16 | 43 | 30 | 16 | 26 | 45+ | 13 | 25 | 6 | 21 | – |
| Onset to discharge (d) | 43 | 48 | 37 | 37 | 34 | 49+ | 20 | 34 | – | 31 | – |
CNI = calcineurin inhibitors; COVID-19 = coronavirus disease 2019; IS = immunosuppression; i.v. = intravenous; IVIG = intravenous immunoglobulin; M = mycophenolate mofetil; Mi = mizoribine; MP = methylprednisolone; n = total number of patients with available data.