Table 5.
Overview and Description of AE Cases
| Case (Sex; Age) | Study | Severity | Description of AE | AE Onset Time After SonoVue® Application | AE Duration, Outcome and Treatment Applied |
|---|---|---|---|---|---|
| 1 (w; 78) | RSA prospective | Mild | Sensation of warmth,dizziness, discomfort; Nausea |
1–2 min. 5–10 min. |
Spontaneously resolved within < 5 min. by resting Fully resolved after 10– 15 min. ➤ No drug treatment/support |
| 2 (w; 34) | HTOWO | Mild | Sensation of warmth, dizziness, discomfort; Subsequent itching, headache |
1–2 min. 3–5 min. |
Spontaneously resolved within< 5 min. by resting Fully resolved after 60– 120 min. ➤ No drug treatment/support |
| 3 (m; 53) | Fractures | Severe | Hypertension, tachycardia, dyspnea Sweating, nausea |
1–2 min. 2–3 min. |
Stabilization after 40 min., fully resolved after 120 min. Fully resolved after 10– 15 min. ➤ Drug treatment/support: Prednisolon 250 mg Dimetindene 4 mg Ringer’s solution 500 mL |
Abbreviations: RSA, reverse shoulder arthroplasty; HTOWO, high tibial open wedge osteotomy.