Table 4.

Genetic Associations of T2DM (Excluding T1DM) and TB-Related SNPs in the UK Biobank (12502 Non-T1DM T2DM Cases, 310267 Controls)

Chromosome	POS	SNP ID	Allelesa	Freqb	Model 1c		Model 2d
					OR (95% CI)	P Value	OR (95% CI)	P Value
6	31628397	rs148844907	T/A	0.01	0.942 (0.843–1.053)	.296	0.945 (0.845–1.056)	.319
6	32390578	rs3135359	T/C	0.73	1.024 (0.990–1.061)	.170	1.024 (0.989–1.060)	.187
6	32433276	rs2894257	G/C	0.51	1.084 (1.050–1.119)	8.65×10–7	1.079 (1.045–1.114)	3.60×10–6
8	131296767	rs4733781	C/A	0.69	1.030 (1.002–1.059)	.036	1.031 (1.003–1.060)	.033
11	32364187	rs2057178	A/G	0.84	0.972 (0.938–1.007)	.115	0.970 (0.936–1.005)	.096
18	20190795	rs4331426	G/A	0.97	0.981 (0.914–1.054)	.608	0.979 (0.911–1.051)	.552

Abbreviations: CHROM, chromosome number; CI, confidence interval; Freq, frequency of effect allele; OR, odds ratio; POS, base pair position (GRCh37/hg19); SNP, single nucleotide polymorphism.

^aThe 2 alleles represent reference/effect alleles.

^bFreq: frequency of effect allele.

^cModel 1: basic adjusted model with age, sex, body mass index, principal components 1–10.

^dModel 2: full adjusted model with age, sex, body mass index, smoking, alcohol, principal components 1–10.