Figure 1. Transcriptional programs induced by isoniazid exposure in log-phase, NRP1 and NRP2 growth states.
The expression pattern of 71 genes induced by isoniazid (INH) treatment in aerobic conditions are clustered alongside the transcriptional activity of these genes after INH exposure in NRP1 and NRP2. The genes are displayed as rows, growth conditions as columns. No genes were significantly differentially expressed in NRP2 after INH treatment. Red coloring signifies induction; blue denotes repression relative to the respective drug-free growth state controls.
†Genes that were also INH-responsive in NRP1. NRP: Nonreplicating persistence.