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. Author manuscript; available in PMC: 2020 Apr 18.
Published in final edited form as: Microb Pathog. 2019 Oct 7;137:103778. doi: 10.1016/j.micpath.2019.103778

Table 1. MCC Cases Tested for MCV T antigen Expression.

Case # Age Sex Site IHC
Treatment Outcome
CD56 CK20 Chromogranin CK7 Synaptophysin Others MCVLT
(CM2B4)
MCVLT
(Ab3)
MCVLT
(PCR)
1 59 M Groin + + + HMWCK- + NK Metastais (LN)
2 37 M Thigh + + + + c-KIT+, MIC2- + + + Rx, Rx-R0 resection NK
3* 37 F Wrist + + MIB1-100- + Excision, R0 resection FOD(21mo)
4 67 M AxillaLN + + + CK+, EMA+, AE1A3+ + + + Excision, CT(Etoposide, Carboplatin) FOD(16mo)
5 74 M Leg + + CK- + NK NK
6 60 F Scalp + + + + CK+,NSE + EMA+,MIB1-80- NT NK NK
7 57 F Nose + + EMA+,CK- + + NT Excision NK
8 64 M Knee + + EMA+, CK+,S100P- NT Excision NK
9 72 M Neck + + AE1/AE3+,c-KIT+ + Excision NK
10 59 M Thumb + + + c-KIT+ NT NT Amputation & CT (Paclitaxel, Carboplatin, Etoposide, Imatinib) Metastasis (Scalp)
11 66 M Thigh + + + + HMB45-,S100P-,AE1/AE3+ + Supportive Care Metastasis (LN & Lung)
12 74 F Knee + + S100P-, GFAP-,AE1/AE3+, EMA-,BCl2+ + NK NK
13 62 F Arm + AE1/AE3+, MIC-2+, Desmin-,Tdt- + + NK NK
14 62 F Thigh + + + MIC2+, AE1/AE3+, Desmin-, MyoD1-, Myogenin- NK NK
15 60 F Neck (Submadibular) + + + + EMA+ NT NK NK
16 50 M Chest wall + + AE1/AE3+, MIC2+, Fli1+,Desmin- NK NK
17 42 M Upper Arm + + + AE1/AE3+, MIC2+, Fli1+,Desmin-, S100P- + + NK NK
18 49 M Inguinal and Gluteal + + MIC2+,Desmin- + NT NT CT Metastais (LN)

Abbreviations: F-female, M-Male,+ -positive, − -negative,NT-Not tested, HMWCK-High molecular weight cytokeratin, EMA-Epithelial membrane antigen, CK- Cytokeratin, AE1/AE3- Pan- Cytokeratin, NSE- Neuron specific enolase, MIB1-Mind Bomb1, S100P–S100 calcium-binding protein P, HMB45-Human melanoma Black, GFAP-Glial fibrillary acid protein, MIC2-Cluster of differentiation 99 (CD99), Tdt-Terminal deoxynucleotidyl transferase, Fli1- Friend Leukemia Integration, * -MCC with coexisting Bowen disease., NK-not known, CT-chemotherapy, FOD-free-of-disease, LN-Lymph Node.