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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Biochim Biophys Acta Gene Regul Mech. 2019 Oct 19;1863(6):194418. doi: 10.1016/j.bbagrm.2019.194418

Figure 3: Distribution of gene-gene Pearson correlations and full order partial correlations.

Figure 3:

Figure (a) shows the distribution of gene-gene Pearson’s correlation coefficients estimated for single-cell RNA sequencing data of melanoma metastases from Tirosh et al. (2016). Figure (b) shows the corresponding distribution of full order partial correlations estimated using the R package GeneNet (Schaefer et al., 2015). The black dashed lines in (a) mark the highest and lowest percentile (99% and 1%) of (anti-)correlations. In (b), the corresponding lines are shown for partial correlations. Notice that for both (a) and (b) the y-axis is on log-scale.