Table 1.
Characteristics of patients with pancreatic cancer and controls
| Discovery set controls (n=245) |
Validation set controls (n=259) |
P Value | All Controls (n=504) |
PDAC (n=245) |
P Value | |
|---|---|---|---|---|---|---|
| Age - mean (SD) | 61.5 (9.5) | 56.4 (10.6) | <0.0001 | 58.9 (10.4) | 67.9 (10.6) | < 0.0001 |
| Race - no. (%) | 1 | 0.0002 | ||||
| White | 232 (94.7) | 244 (94.2) | 476 (94.4) | 211 (86.1) | ||
| Other | 13 (5.3) | 15 (5.8) | 28 (5.6) | 34 (13.9) | ||
| Sex - no. (%) | 0.0157 | 0.0231 | ||||
| Female | 121 (49.4) | 156 (60.2) | 277 (55.0) | 113 (46.1) | ||
| Male | 124 (50.6) | 103 (39.9) | 227 (45.0) | 132 (53.9) | ||
| BMI - mean (SD) | 27.4 (4.7) | 27.5 (5.0) | 0.5964 | 27.4 (4.8) | 25.6 (4.1) | < 0.0001 |
| Smoker - no. (%) | 0.8216 | 0.0507 | ||||
| Not current smoker | 236 (96.3) | 248 (95.8) | 484 (96.0) | 224 (91.4) | ||
| Current smoker | 9 (3.7) | 11 (4.2) | 20 (4.0) | 18 (7.3) | ||
| Diabetic~ - no. (%) | 1 | < 0.0001 | ||||
| No | 228 (93.1) | 240 (92.7) | 36 (7.1) | 90 (54.5) | ||
| Yes | 17 (6.9) | 19 (7.3) | 468 (92.9) | 75 (45.5) | ||
| Stage (8th AJCC) | ||||||
| I A | 18 (7.3) | |||||
| I B | 31 (12.6) | |||||
| IIA | 4 (1.6) | |||||
| IIB | 106 (43.3) | |||||
| III | 86 (3.5) |
Abbreviations: PDAC, pancreatic ductal adenocarcinoma; SD, standard deviation; BMI, body mass index; ~status not known for some cases