Table 2.
SNP stratified tumor marker levels in discovery set controls
| CA19-9 | number | Mean (U/mL) | SD | Mean +/− 3 SD* |
|---|---|---|---|---|
| FUT3 (−/−) | 26 | 2.7 | 2.3 | 9.5 |
| FUT3 (+/−) | 85 | 7.4 | 5.4 | 23.5 |
| FUT3 (+/+) | 75 | 10.9 | 9.1 | 38.1 |
| FUT2 (−/−) | 59 | 22.8 | 14.6 | 66.6 |
| Uniform diagnostic cut-off (Not SNP-stratified) | 245 | 11.7 | 11.5 | 46.1 |
| CEA | number | Mean (ng/mL) | SD | Mean +/− 3 SD* |
| FUT2+/blood B | 26 | 1.2 | 1.8 | 6.6 |
| FUT2+/non-blood B | 151 | 0.7 | 0.7 | 2.8 |
| FUT2 −/− /blood B | 4 | 1.5 | 0.9 | 4.3 |
| FUT2 −/− /non blood B | 55 | 1.3 | 0.9 | 4.0 |
| smoker | 9 | 1.7 | 0.8 | 4.2 |
| Uniform diagnostic cut-off (Not SNP-stratified) | 245 | 0.9 | 1.0 | 3.9 |
| CA125 | number | Mean (U/mL) | SD | Mean +/− 3 SD* |
| GAL3ST2 rs12469459-AA | 101 | 7.4 | 5.0 | 22.3 |
| GAL3ST2 rs12469459-TT | 90 | 5.2 | 3.7 | 16.2 |
| GAL3ST2 rs12469459-TT | 26 | 4.3 | 2.1 | 10.7 |
| Uniform diagnostic cut-off (Not SNP-stratified) | 217 | 6.1 | 4.4 | 19.2 |