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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2020 Jan 22;199:105603. doi: 10.1016/j.jsbmb.2020.105603

Figure 4. Dietary vitamin D3 alters T cell levels in tongue tissues.

Figure 4.

(A) Photomicrographs of CD3 stained sections (40X, scale bar - 50μm) of normal tongue epithelium, dysplasia and OSCC of a representative mouse from each diet group. (B-D) Counts of CD3+ T cells in normal, moderate dysplasia and severe dysplasia + OSCC tissues in mice across the three diets. (E) CD3+ T cell counts in SD+OSCC lesions in the three vitamin D3 diet cohorts. Mice on 100 IU showed significant increase in CD3+ T cell counts in SD+ OSCC compared to mice on 25 IU or 10000 IU. Reported values represent mean ± standard error. *p < 0.05, ** p <0.01