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. Author manuscript; available in PMC: 2021 Apr 15.
Published in final edited form as: Alcohol Clin Exp Res. 2020 Apr 15;44(4):900–918. doi: 10.1111/acer.14315

Table 5.

Proximal Maternal Risk Factors for FASD: Combined Sample Data for Physical, Demographic, Childbearing, Alcohol and Drug Use from a Rocky Mountain Region City

Children with
FASD
(n=35)
Randomly-Selected
Control Children
(n=197)
χ2
or
t-test
p-value
Mean (SD) Mean (SD)
Alcohol Use – Before and During Pregnancy
 Drank before pregnancy (% Yes) 78.1 60.3 3.719 .054
 # of drinks consumed on usual drinking day before pregnancy1 5.3 (3.1) 3.2 (2.6) 3.510 .001**
Mdn = 4.0 Mdn = 2.0 - -
 Usual frequency – before pregnancy1
  Everyday or almost everyday 8.0 4.3
  3-4 times per week 16.0 2.2
  1-2 times per week 48.0 39.2
  2-3 times per month 16.0 15.2
  1 time per month or less 12.0 39.1 7.928 .094
 Drank in 1st trimester (% Yes) 18.2 6.3 5.335 .033A,*
# of drinks on usual drinking day1 −1st 4.1 (2.0) 2.5 (2.2) 1.341 .201
 Usual frequency1 – 1st
  Everyday or almost everyday 0.0 9.1
  3-4 times per week 0.0 9.1
  1-2 times per week 0.0 18.2
  2-3 times per month 0.0 0.0
  1 time per month or less 100.0 63.6 3.955 .683
 Drank in 2nd trimester (% Yes) 15.2 3.7 7.262 .019A,*
 # of drinks on usual drinking day1 - 2nd 5.3 (2.9) 1.2 (0.6) 2.451 .130
 Usual frequency1 – 2nd
  Everyday or almost everyday 0.0 14.3
  3-4 times per week 0.0 14.3
  1-2 times per week 0.0 0.0
  2-3 times per month 0.0 0.0
 1 time per month or less 100.0 71.4 5.102 .531
 Drank in 3rd trimester (% Yes) 6.1 3.2 .685 .337A
 # of drinks on usual drinking day1 - 3rd -- -- 1.1 (0.5) -- --
 Usual frequency1 – 3rd 0.0
  Everyday or almost everyday 16.7
  3-4 times per week 0.0
  1-2 times per week 0.0
  2-3 times per month 0.0
  1 time per month or less -- 0.0 -- --
Alcohol Use - Current
 Drink in past 30 days (% Yes) 64.5 69.0 .249 .618
 Binge 5+ in past month (% Yes) 29.0 27.7 .023 .880
 Why usually drink: because others drink 6.5 7.6 .052 1.00A
 Why usually drink: to feel less anxious 9.7 1.6 6.333 .040A,*
 Current drinking problem (% Yes) 6.3 1.1 4.059 .104A
 Recovering drinker (% Yes) 15.8 4.8 3.242 .104A
Drug Use
 Used tobacco – during pregnancy (% Yes) 17.6 20.3 .129 .819A
 Used any drugs in pregnancy (% Yes) 8.8 6.2 .337 .472A
 Abused prescription – during pregnancy 2.9 2.6 .015 1.00A
 Used marijuana – during pregnancy (% Yes) 8.8 5.7 .499 .455A
 Used marijuana & alcohol – during pregnancy (% Yes) 6.3 1.6 2.620 .157A
 Used club drugs – during pregnancy (% Yes) 2.9 0.5 1.929 .279A
 Used cocaine - during pregnancy (% Yes) 2.9 1.0 .804 .387A
Used methamphetamine – pregnancy (% Yes) 2.9 2.6 .015 1.00A
 Used tobacco – in lifetime
  Yes, within last 30 days 26.5 27.5
  Yes, in lifetime 35.3 29.0
  Never 38.2 43.5 1.282 .527
 Used any drug in lifetime (% Yes) 67.6 49.7 3.721 .054
 Used marijuana – in lifetime (% Yes) 67.6 47.6 4.620 .032*
 Used methamphetamine – in lifetime (% Yes) 20.0 13.1 1.162 .294A
 Used heroin – in lifetime (% Yes) 5.9 3.8 .313 .634A
 Used club drugs – in lifetime (% Yes) 5.9 4.3 .160 .656A
 Used crack/cocaine – in lifetime (% Yes) 14.7 10.8 .446 .555A
 Abused pain killers – in lifetime (% Yes) 5.9 5.3 .016 1.00A
1.

Among women who drank in that specific time period.

2.

A collateral interview confirmed alcohol consumption but with unknown quantity and/or frequency.

A.

Fisher’s Exact Test

*

Significant at 0.05

**

Significant at Bonferroni-adjusted level: Bonferroni-adjusted significant levels: alcohol use – before and during pregnancy = 0.004; alcohol use – current = 0.008; other drug use = 0.003.