Table 5.

Summary of studies examining fetal alcohol spectrum disorders and hippocampal volume

Persisted after ICV	N	Sex	Ethnic group	Age	Groups	MRI methods
Archibald et al. 2001	67	Both	Not reported	7–24 years	FAS vs. PAE vs. Control	Manual tracing
Nardelli et al. 2011	28	Both	Mostly Caucasian, some aboriginal	6–17 years	FASD vs. Controls	FreeSurfer
Willoughby et al. 2008	37	Both	Not reported	9–15 years	FASD vs. Controls	Manual tracing
Did not persist after ICV
Astley et al. 2009	81	Both	Mostly Caucasian, some African American and Native American	M = 12, SD = 2	FAS/PFAS vs. SE/AE vs. ND/AE vs. Controls	Manual tracing
Coles et al. 2011	92	Both	Mostly African American	M = 21, SD = 2	Dysmorphic vs. ARND vs. Controls	FreeSurfer
Joseph et al., 2014	21	Both	Cape Coloured	M = 11.5, SD = 1.2	FAS/PFAS vs. Controls	Manual tracing
Riikonen et al., 2005	22	Both	Not reported	5–16 years	FAS/FAE vs. Controls with indication for MRI	EasyMeasure
Roussotte et al. 2012	99	Both	Multi-site study--Los Angeles and San Diego, mostly non-Hispanic Caucasian; South Africa site was Cape Coloured	M = 13; SD = 1.8	FASD vs. Controls	FreeSurfer