Table 1.
Membrane properties of interneuron populations recorded
| Interneuron type | Input Resistance (MΩ) | Action Potential Threshold (mV) | Maximum firing (Hz) | Adaptation ratiod | Sag ratioe | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Feedback Interneuron (7) | 664.7 ± 73.6 ***a | − 53.4 ± 0.7 | 35.4 ± 5.9 | 3.11 ± 0.5***b | 1.09 ± 0.04 | ||||||
| Non-feedback Interneuron (7) | 301 ± 39.7 | − 41.7 ± 1.3 | 51.0 ± 5.2 | 1.41 ± 0.1 | 1.03 ± 0.01 | ||||||
| SOM + Interneuron (11) | 397.7 ± 57.9*c | − 44.5 ± 2.1 | 45.4 ± 4.2 | 2.14 ± 0.4 | 1.18 ± 0.10 | ||||||
| BL-responsive SOM + interneuron (5) | BL-Unresponsive SOM + interneuron (6) | 552.4 ± 79.7 | 268.8 ± 27.8## | − 51.5 ± 0.8 | − 38.7 ± 1.0### | 38.6 ± 2.85 | 51.0 ± 6.82 | 3.21 ± 0.48 | 1.25 ± 0.28## | 1.38 ± 0.19 | 1.01 ± 0.01 |
| PV + Interneuron (9) | 250 ± 33.6 | -39.7 ± 1.5 | 48.8 ± 5.3 | 1.29 ± 0.1 | 1.01 ± 0.01 | ||||||
Data are expressed as Mean ± SEM
***a, ***bShows the marked groups significantly differing from all other groups (p < 0.005)
*cMarks a significant difference between SOM+ and PV+ interneurons. Moreover, # symbol indicates significant differences between BL-responsive and BL-unresponsive SOM+ interneurons with ## indicating a p < 0.01 and ### indicating a p < 0.001
dInterval of last two spikes/interval of first two spikes at half-maximal firing
eLargest decrease of voltage/steady state voltage after a current injection that brings the neuron’s steady state voltage nearest to − 90 mV during the V–I curve acquisition procedure