Table 3.
Results regarding differential diagnosis, severity of AD, etiology and physiopathology, comorbidities, and health-related quality of life.
| Item | Consensus (%) | Majority (%) | Discrepancy (%) |
|---|---|---|---|
| Differential diagnosis | |||
| (i) In certain situations, skin biopsy should be considered to exclude other conditions, such as early stage T-cell cutaneous lymphoma, psoriasis, or dermatitis herpetiformis | 99.1 | ||
| Severity of AD | |||
|
| |||
| (i) The SCORAD index is used to quantify the severity of the disease in order to assess the comparative efficacy of treatments and progression of the disease in routine clinical practice | 86.7 | ||
| (ii) The EASI score is a validated scale that is not used in routine clinical practice | 58.1 | ||
|
| |||
| Etiology and physiopathology | |||
| (i) A high percentage of patients with AD also present food allergy, allergic rhinitis, or asthma | 94.4 | ||
| (ii) Treatments oriented to increase filaggrin expression can be useful in the management of AD in a particular group of patients | 93.3 | ||
| (iii)Currently there is an unmet need in the treatment of moderate-severe AD | 98.4 | ||
| (iv) Biologic drugs are especially promising for adult patients with moderate or severe forms of the disease | 89.6 | ||
|
| |||
| Comorbidities of AD | |||
| (i) AD in adults is frequently associated with allergic comorbidities | 78.1 | ||
| (ii) AD in children is frequently associated with allergic comorbidities | 91.4 | ||
| (iii) The relative risk of suffering from immune-mediated inflammatory diseases such as rheumatoid arthritis and chronic inflammatory bowel disease is higher in patients with AD than in the general population | 43.8∗ | ||
| (iv) Children with AD are more prone to suffer from mental disorders such as depression, anxiety, and behavior disorders | 84.8 | ||
|
| |||
| Health-related quality of life | |||
| (i) AD causes considerable psychological anxiety and results in a dramatic impact on the quality of life for both patients and their families | 91.2 | ||
| (ii) The usefulness of PO-SCORAD for the self-assessment of AD in children suggests the importance of integrating the perspectives of the physician and the patient in the management of AD | 91.2 | ||
AD: atopic dermatitis; SCORAD: scoring atopic dermatitis; EASI: eczema area and severity index; PO-SCORAD: patient-oriented SCORAD. ∗43.8% neither agree nor disagree.