Table 4.
Effect of LeGFS on the body development of offspring.
Control | D200 | D500 | D800 | D1000 | |
---|---|---|---|---|---|
Incisor eruption | PN8 ± 0 | PN9 ± 0∗∗∗ | PN9 ± 0.1∗∗∗ | PN9 ± 0.1∗∗∗ | PN9 ± 0∗∗∗ |
Appearance of hair | PN6 ± 0 | PN7 ± 0.24∗∗∗ | PN7 ± 0.20∗∗∗ | PN8 ± 0.24∗∗∗ | PN8 ± 0.20∗∗∗ |
Opening of auditory canal | PN12 ± 0 | PN13 ± 0.20∗∗ | PN13 ± 0.20∗∗ | PN13 ± 0.24∗∗∗ | PN13 ± 0.24∗∗∗ |
Eye opening | PN14 ± 0 | PN14 ± 0.44 | PN14 ± 0.54 | PN15 ± 0.40∗∗∗ | PN16 ± 0.51∗∗∗ |
Results are presented as mean ± SEM. ∗∗p < 0.01, ∗∗∗p < 0.001 vs. control (ANOVA test). PN: postnatal day; D: dose (mg/kg).