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ISL inhibited the proliferation of VSMCs. (a) Identification of VSMCs isolated from C57BL/6J mice aortas (staining ×400). (b) CCK8 assay of the proliferation of VSMCs. Values are expressed as means ± SD (n = 5). Control: control group; Ang II: Ang II group; 10ISL: Ang II 10−6 mol/l + 10 μmol/l ISL group; 20ISL: Ang II 10−6 mol/l + 20 μmol/l ISL group; 40ISL: Ang II 10−6 mol/l + 40 μmol/l ISL group; 60ISL: Ang II 10−6 mol/l + 60 μmol/l ISL group.
