Table 2.
Proportional Reporting Ratios (PRR) and 95% confidence intervals (95% CI) for each exposure and event of interest.
| Drug of interest | Adverse event of interest | PRR | Lower 95% CI | Upper 95% CI | |
|---|---|---|---|---|---|
| Hydroxychlorquine/Chloroquine (HCQ/CQ) | Death | 0.46 | 0.44 | 0.47 | |
| TdP/QT prolongation | 1.43 | 1.29 | 1.59 | ||
| Accidents/Injuries | 1.73 | 1.68 | 1.77 | ||
| Depression | 0.97 | 0.92 | 1.02 | ||
| Azithromycin + HCQ/CQ | Death | 0.66 | 0.48 | 0.90 | |
| TdP/QT prolongation | 3.77 | 1.80 | 7.87 | ||
| Accidents/Injuries | 1.94 | 1.47 | 2.55 | ||
| Depression | 2.28 | 1.54 | 3.38 | ||
| Amoxicillin + HCQ/CQ | Death | 0.56 | 0.42 | 0.74 | |
| TdP/QT prolongation | NA | NA | NA | ||
| Accidents/Injuries | 1.89 | 1.50 | 2.38 | ||
| Depression | 1.98 | 1.40 | 2.82 | ||
| Azithromycin | Death | 0.81 | 0.79 | 0.83 | |
| TdP/QT prolongation* | 4.10 | 3.80* | 4.42 | ||
| Accidents/Injuries | 1.18 | 1.13 | 1.22 | ||
| Depression | 1.29 | 1.22 | 1.37 | ||
| Amoxicillin | Death | 0.9 | 0.88 | 0.92 | |
| TdP/QT prolongation | 1.65 | 1.51 | 1.79 | ||
| Accidents/Injuries | 1.04 | 1.01 | 1.07 | ||
| Depression | 0.99 | 0.94 | 1.04 | ||
Note: For pharmacovigilance safety signal detection, the lower limit of the 95% CI is often interpreted as significant if ≥ 2. Those values are marked with a asterisk (*).