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. 2007 Oct 26;9(12):1080–1086. doi: 10.1002/jgm.1111

Figure 1.

Figure 1

Composition of the 8–17 and 10–23 catalytic motifs. The DNAzyme (lower strand) binds the RNA substrate (top strand) through Watson–Crick pairing. Cleavage occurs at the position indicated by the arrow. R = A or G; Y = U or C