Table I.
Clinical and Functional Baseline Characteristics of 51 Prospectively Studied Patients
| No reported AECOPD (n = 26) | 1 reported AECOPD (n = 11) | >2 reported AECOPD (n = 14) | |
|---|---|---|---|
| Age, year | 66 ± 8 | 60 ± 9 | 60 ± 8* |
| Male gender, % | 84 | 73 | 86 |
| Current smoker, % | 23 | 55 | 29 |
| Smoking history, pack‐year | 43 ± 20 | 57 ± 24 | 41 ± 15 |
| Chronic bronchitis, % | 54 | 82 | 79 |
| Influenza vaccination, % | 68 | 56 | 89 |
| Pneumococcus vaccination, % | 47 | 40 | 50 |
| FEV1, % predicted | 45 ± 8 | 44 ± 13 | 41 ± 16 |
| FVC, % predicted | 75 ± 14 | 69 ± 9 | 72 ± 15 |
| FEV1/FVC, % | 47 ± 9 | 49 ± 14 | 45 ± 14 |
| BMI, kg/m2 | 28 ± 9 | 27 ± 6 | 27 ± 9 |
| PaO2, mmHg | 74 ± 9 | 74 ± 6 | 74 ± 13 |
| PaCO2, mmHg | 41 ± 5 | 41 ± 5 | 42 ± 5 |
| pH | 7.41 ± 0.04 | 7.42 ± 0.02 | 7.41 ± 0.04 |
| Inhaled corticosteroid,% | 88 | 81 | 93 |
| Long‐acting β2‐agonist, % | 96 | 91 | 100 |
| Short‐acting bronchodilator, % | 50 | 91 | 71 |
| Long term oxygen therapy, % | 4 | 9 | 0 |
AECOPD, acute exacerbation of chronic obstructive pulmonary disease.
Data are presented as mean ± SD.
*
P < 0.05 versus no AECOPD.