Table 1.
Clinical, demographic, and serological characteristic of infants with bronchiolitis from single virus versus multiple viruses
| Variables | Single infection n = 431 infants | Co‐infection n = 55 infants | P value |
|---|---|---|---|
| Sex (male) | 228 (52.9%) | 35 (63.6%) | ns |
| Age (months) median (range) | 2.0 (0.23‐11.17) | 2.13 (0.43‐11.10) | ns |
| Birth weight (kg) median (range) | 3.20 (1.87‐4.5) | 3.12 (2.08‐4.14) | ns |
| Breastfeeding (months) median (range) | 1.04 (0‐10) | 1.15 (0‐7) | ns |
| Exposure to smoke | 200 (46.9%) | 26 (48.1%) | ns |
| Family history of asthma | 95 (22.2%) | 19 (34.5%) | 0.043 * |
| Family history of atopy | 165 (38.6%) | 15 (27.3%) | ns |
| Fever | 183 (42.6%) | 16 (29.1%) | 0.05 * |
| Clinical severity score median (range) | 4 (0‐8) | 4 (0‐8) | ns |
| O2 therapy | 98 (23.2%) | 13 (23.6%) | ns |
| Days hospitalization median (range) | 5 (1‐45) | 4 (2‐12) | ns |
| PICU admission | 48 (11.2%) | 13 (23.6%) | ns |
| Total white blood cell count (n/mm3) median (range) | 10 770 (1750‐31 750) | 9870 (4380‐22 600) | ns |
| Blood neutrophils (n/mm3) median (range) | 3970 (510‐18 810) | 3080 (569‐11 179) | 0.005 ** |
| Blood lymphocytes (n/mm3) median (range) | 4670 (110‐15 150) | 4767 (1220‐12 040) | ns |
| Blood eosinophils > 400 /mm3 | 34 (8.0%) | 5 (9.1%) | ns |
| Serum sodium (mmoL/L) median (range) | 137 (133‐159) | 139 (133‐146) | 0.012 ** |
| C‐reactive protein (mg/dL) median (range) | 0.46 (0‐13.51) | 0.25 (0‐16.98) | 0.012 ** |
| Chest X‐ray | |||
| Air trapping | 183 (52.9%) | 22 (50.0%) | ns |
| Infiltrates/atelectases | 197 (56.9%) | 27 (61.4%) | ns |
| Recurrent wheezing at 12 months | 186 (53.0%) | 19 (43.2%) | ns |
| Recurrent wheezing at 24 months | 131 (44.7%) | 15 (40.5%) | ns |
| Recurrent wheezing at 36 months | 93 (38.0%) | 11 (43.2%) | ns |
*
P value by χ 2 test.
**
P value by non parametric median test.