Table 2.
Clinical, demographic, and serological characteristic of infants with respiratory syncytial virus (RSV) bronchiolitis versus RSV coinfection bronchiolitis
| Variables | RSV n = 320 infants | RSV coinfection n = 45 infants | P value |
|---|---|---|---|
| Sex (male) | 178 (55.6%) | 31 (69.8%) | ns |
| Age (months) median (range) | 2.03 (0.23‐9.87) | 2.10 (0.43‐11.10) | ns |
| Birth weight (kg) median (range) | 3.26 (2.03‐4.5) | 3.14 (2.08‐4.14) | ns |
| Breastfeeding (months) median (range) | 1.13 (0‐9.21) | 1.06 (0‐5.18) | ns |
| Exposure to smoke | 148 (46.8%) | 20 (44.4%) | ns |
| Family history of asthma | 72 (22.7%) | 15 (17.2%) | ns |
| Family history of atopy | 124 (39.1%) | 12 (26.7%) | ns |
| Fever | 138 (43.1%) | 13 (28.9%) | 0.069 * |
| Clinical severity score median (range) | 4 (0‐8) | 4 (1‐8) | ns |
| O2 therapy | 81 (25.9%) | 13 (28.9%) | ns |
| Days hospitalization median (range) | 5 (1‐27) | 5 (2‐12) | ns |
| PICU admission | 38 (11.9%) | 6 (13.3%) | ns |
| Total white blood cell count (n/mm3) median (range) | 10 310 (1750‐29 300) | 9510 (4380‐22 600) | ns |
| Blood lymphocytes (n/mm3) median (range) | 4533 (1570‐12 010) | 4530 (1220‐11 707) | ns |
| Blood neutrophils (n/mm3) median (range) | 3800 (510‐18 810) | 3080 (569‐11 179) | ns |
| Blood eosinophils > 400/mm3 | 23 (7.3%) | 4 (8.9%) | ns |
| Serum sodium (mmoL/L) median (range) | 137 (123‐159) | 139 (133‐145) | ns |
| C‐reactive protein (mg/dL) median (range) | 0.44 (0‐13.51) | 0.23 (0‐16.98) | 0.011 ** |
| Chest X‐ray | |||
| Air trapping | 142 (54.4%) | 18 (48.6%) | ns |
| Infiltrates/atelectases | 156 (59.7%) | 24 (64.9%) | ns |
| Recurrent wheezing at 12 months | 131 (49.6%) | 13 (37.1%) | ns |
| Recurrent wheezing at 24 months | 89 (40.6%) | 13 (31.0%) | ns |
| Recurrent wheezing at 36 months | 66 (37.1%) | 5 (25.0%) | ns |
*
P value by χ 2 test.
**
P value by non parametric median test.