Table 4.
Clinical, demographic, and serological characteristic of infants with hRV bronchiolitis versus RSV + hRV co‐infection
| RSV n = 320 infants | hRV n = 60 infants | hRV + RSV n = 20 infants | P value | |
|---|---|---|---|---|
| Sex (male) | 178 (55.6%) | 31 (51.7%) | 13 (57.9%) | ns |
| Age (months) median (range) | 2.03 (0.23‐9.87) | 1.48 (0.27‐9.17) | 2.03 (0.80‐5.60) | ns |
| Birth weight (kg) median (range) | 3.26 (2.03‐4.5) | 3.06 (1.88‐4.00) | 3.30 (2.52‐4.14) | 0.017 ** |
| Breastfeeding (months) median (range) | 1.13 (0‐9.21) | 1 (0‐9) | 1.15 (0‐5.18) | ns |
| Exposure to smoke | 148 (46.8%) | 29 (48.3%) | 10 (47.6%) | ns |
| Family history of asthma | 72 (22.7%) | 8 (13.3%) | 8 (38.1%) | 0.05 * |
| Family history of atopy | 124 (39.1%) | 24 (40.0%) | 5 (23.8%) | ns |
| Fever | 138 (43.1%) | 19 (31.7%) | 3 (14.3%) | 0.012 * |
| Clinical severity score median (range) | 4 (0‐8) | 3 (0‐8) | 4 (1‐8) | ns |
| O2 therapy | 81 (25.9%) | 11 (18.3%) | 9 (42.9%) | ns |
| Days of hospitalization median (range) | 5 (1‐27) | 5 (2‐16) | 5 (3‐9) | ns |
| PICU admission | 38 (11.9%) | 8 (13.6%) | 2 (9.5%) | ns |
| Total white blood cell count (n/mm3) median (range) | 10 310 (1750‐29 300) | 13 050 (3500‐31 750) | 9840 (4380‐20 710) | ns |
| Lymphocytes (n/mm3) median (range) | 4533 (1570‐12 010) | 4989 (1100‐15 150) | 4770 (1220‐11 115) | ns |
| Neutrophils (n/mm3) median (range) | 3800 (510‐18 810) | 5185 (570‐17 029) | 3080 (990‐7560) | 0.008 ** |
| Eosinophils > 400/mm3 | 23 (7.3%) | 11 (18.3%) | 1 (4.8%) | 0.021 * |
| Sodium (mmoL/L) median (range) | 137 (123‐159) | 136 (131‐146) | 139 (133‐144) | ns |
| C‐RP (mg/dL) median (range) | 0.44 (0‐13.51) | 0.6 (0.03‐8.71) | 0.21 (0‐1.77) | 0.016 ** |
| Chest X‐ray | ||||
| Air trapping | 142 (54.4%) | 23 (48.9%) | 10 (52.6%) | ns |
| Infiltrate/atelectasis | 156 (59.7%) | 21 (44.7%) | 10 (52.6%) | ns |
| Recurrent wheezing at 12 months | 131 (49.6%) | 32 (65.3%) | 8 (42.1%) | ns |
| Recurrent wheezing at 24 months | 89 (40.6%) | 25 (56.8%) | 5 (33.3%) | ns |
| Recurrent wheezing at 36 months | 66 (37.1%) | 16 (40%) | 2 (22.2%) | ns |
*
P value by χ 2 test.
**
P value by non parametric median test.